hsa-mir-4753-3p _LIHC.png
PIK3CB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004985
Fusion event
HBV-PIK3CB integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
295
Orient
-
Integrated sequence
GTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACG| |TGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTATCGCTGGATGTGTCTGCGGCGTTTTA
Host Sequence
Chromosome
chr3
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
138475113/138756271 (Hg38)
End
138475113/138756271 (Hg38)
Orient
+
Location type
Intron
Target gene
PIK3CB
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-101-3p ; hsa-mir-125b-5p ; hsa-mir-1207-3p ; hsa-mir-4424 ; hsa-mir-4682 ; hsa-mir-6787-3p ; hsa-mir-6830-5p ; hsa-mir-8077 ; hsa-mir-130b-5p ; hsa-mir-2117 ; hsa-mir-3124-3p ; hsa-mir-4277 ; hsa-mir-4753-3p ; hsa-mir-6809-3p
Nearest miRNA
hsa-let-7g/Upstream/4318365; hsa-mir-1224/Downstream/12809605;
Nearest TSS
ENST00000440867/Upstream/13490; ENST00000498709/Downstream/3088;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/146928, chr3-CpG: 90/Downstream/78046
Junction sequence
AT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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