Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004990
Fusion event
HBV-WDR49 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1889
Orient
-
Integrated sequence
TAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT| |GGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCT
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
End
167294437/167576649 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-let-7g/Upstream/3405093; hsa-mir-1224/Downstream/975205;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/196239, chr3-CpG: 37/Downstream/157939
Upstream sequence
AAATATGGTAAAGAACATTAAACAACCCATGGTCTGGGTCTTAATCTGGTGCTCACagtgatcattcagtctctgctgcataccaccagggcacggaact
Downstream sequence
ttgctggctttgaagagggccatgatccaaggaagcttgaaaagacaaaggaatggtttctcccccagagccaccagaaaggatgagactcatgtcaaat
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).