Basic Information
VIS ID
TVIS10005038
Fusion event
HBV-LOC107986454 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1
Orient
-
Integrated sequence
C| |TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTA
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
141202371/141822806 (Hg38)
End
141202371/141822806 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986454
Nearest miRNA
hsa-mir-10397/Upstream/1174880; hsa-mir-103a-1/Downstream/1857054;
Nearest TSS
ENST00000502646/Upstream/140585; ENST00000506775/Downstream/3519;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/69035, chr5-CpG: 102/Downstream/26559
Junction sequence
TTCCACTGCATGGCCTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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