Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005081
Fusion event
HBV-MTMR8 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
579
Orient
-
Integrated sequence
TACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACAAAACC| |TTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTA
Host Sequence
Chromosome
chrX
Cytoband
q11.2
Reference genome
Start
End
63602126/64382246 (Hg38)
Orient
+
Location type
Intron
Target gene
Nearest miRNA
hsa-let-7f-2/Upstream/596159; hsa-mir-105-1/Downstream/1636624;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/175936, chrX-CpG: 34/Downstream/12831
Upstream sequence
ttgtacatagttttggatacatgtatatatttggatacatatacacaatgtgtaatgatcaagtcagggtaatcaggatacccatcacttcaaatatttg
Downstream sequence
cttccatttgtttgtatcctcttttatttcgttgagcagtggcttgtagttctccttgaagaggtccttcacgtcccttgtaagttggattcctaggtat
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).