Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005082
Fusion event
HBV-MTMR8 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1816
Orient
+
Integrated sequence
GTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGT
Host Sequence
Chromosome
chrX
Cytoband
q11.2
Reference genome
Start
End
63602156/64382276 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-let-7f-2/Upstream/596189; hsa-mir-105-1/Downstream/1636594;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/175966, chrX-CpG: 34/Downstream/12801
Upstream sequence
cagctgctgatagcatctggcctttaagaaggctcaaaaatttaaagttaataatgctagatgcaattgcatatggggtgtcccatagtcactgtttctc
Downstream sequence
gttgagcagtggcttgtagttctccttgaagaggtccttcacgtcccttgtaagttggattcctaggtattttattctctttgaagcaattgtgaatggg
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).