Basic Information
VIS ID
TVIS10005094
Fusion event
HBV-chr11 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1777
Orient
+
Integrated sequence
CAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGG| |AGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGC
Host Sequence
Chromosome
chr11
Cytoband
p14.3
Reference genome
End
25626730/25605184 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/2185994; hsa-let-7a-2/Downstream/1909786;
Upstream sequence
cccaagtccccaaagtccattgtagctttcttatgcctttgtgtcgtcataccttagctccctcttgtgagtgagaacacacaatgtttgattgtccatt
Downstream sequence
tcttcacttagaatagtggtgttcaattccatccaagttgctgtgaatgccattctttcattcttttttatgactgagtagtattccatggggtgtgtgt
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate