Fusion event
HBV-chr11 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGG| |AGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGC
End
25626730/25605184 (Hg38)
Nearest miRNA
hsa-mir-210/Upstream/2185994; hsa-let-7a-2/Downstream/1909786;
Upstream sequence
cccaagtccccaaagtccattgtagctttcttatgcctttgtgtcgtcataccttagctccctcttgtgagtgagaacacacaatgtttgattgtccatt
Downstream sequence
tcttcacttagaatagtggtgttcaattccatccaagttgctgtgaatgccattctttcattcttttttatgactgagtagtattccatggggtgtgtgt
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).