Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005105
Fusion event
HBV-TTBK2 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1761
Orient
+
Integrated sequence
ACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAA| |AGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACT
Host Sequence
Chromosome
chr15
Cytoband
q15.2
Reference genome
Start
End
43086303/42794105 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-1233-1/Upstream/594439; hsa-mir-10393/Downstream/999554;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/56684, chr15-CpG: 88/Downstream/126113
Junction sequence
TAATCTTTGTACTA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).