Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005109
Fusion event
HBV-ZNF768 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1824
Orient
-
Integrated sequence
AAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAA
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
Start
End
30538356/30527035 (Hg38)
Orient
-
Location type
Promoter
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/23034; hsa-mir-11401/Downstream/348231;
Nearest CpG islands
chr16-CpG: 142/Target, None/Upstream, None/Downstream
Upstream sequence
GGTGAGGACCGGACGCCCCGGAGCCCGCGGGGCTACCGGGGCAGTGTGTGTGCCTATGTTCTAGGTCTCCGTCCCTCCAGAGGCCCGTCTGTCCATCTCC
Downstream sequence
CGGGCCCCGCGTCGTCGGTGCGTGTGGCCAAGGGCGAGGCGACAAGCGAGACCAAGGTCAGCGAGAAGGAGCGACGCTTCCCGGCGCCAGCGGGGGCGGT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).