Fusion event
HBV-ZNF233 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGG| |GAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTG
End
44766028/44261875 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10395/Upstream/1910670; hsa-let-7e/Downstream/391811;
Upstream sequence
cgagtagctgggattacagatgcccgccaccatgcctggctaatttttgtatttttaggagagatgaggtttcatcatgttggccaggctggtctcgaac
Downstream sequence
tcgtgacctcaagtgatctgcctgccttgacctcctaaagtgctgggattacaggcgtgagccactgcgcctggccTAATGATTTCACTTTTAAGGATGA
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).