FLNB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005133
Fusion event
HBV-FLNB integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2107
Orient
+
Integrated sequence
TCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCC| |ACCTGGGTGGGAAGTAATTTGGAAGACCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATATGGGCCTAAAAATCAGACAACTATTGTGGT
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
End
58045071/58059344 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-let-7g/Upstream/2206750; hsa-mir-12124/Downstream/2558461;
Upstream sequence
TGTACAAACTGCTTAATTCTCATATTTACGTATTCCAATGCAACATTACATAAGAAATAAGGACTATTAGAGGTATTAATTAGATAATTTGGTAAAGTAA
Downstream sequence
tttagtaaataggccaggtggtaAGAGGAGAGAGCCTTGTCTGTGAGTGTGGTCTAGGGGGATGCTGGACCTAGCTTTTCAGAGCTAGGTTCAGGCAGAG
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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