Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005170
Fusion event
HBV-FCRL5 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1941
Orient
+
Integrated sequence
TCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGA| |GTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACAT
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
End
157499609/157529819 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/593575; hsa-mir-1182/Downstream/2370160;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/334474, chr1-CpG: 28/Downstream/449111
Upstream sequence
aaaccaaacattgtatgttctcacttatcagtgggagctaagctatgaggacgcaaaggcctaagcataatataatagattctggggattcagtggaaga
Downstream sequence
gtgagagtggggtgatggataaagtactacacactgggttcagtgtacactgctctggcaacgagtgcaccaaaatctcggaaattactactaaagaagt
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).