Fusion event
HBV-chr1 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CAACCCCCACTGGATGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTG| |TTTTGCTCGCAGCCGGTCTGGAGCAAAACTTATCGGGACTGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTCCCATGGCTGCTCGGGTGTGCT
End
248878329/248715028 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/1512968; hsa-mir-3124/Downstream/111349;
Upstream sequence
ttattattattaagtttttgtttgcttaggggaaaaaccaaaattaaaagaatttttttatttaaggttattacatttgtgtatctttccgtatgggctt
Downstream sequence
ttagagtcattgtgacattgagttacagagctttgactcctgggtctaaaaaggacaccaagttctgctaaatcttaaacactgacaggaattaaagcct
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).