VISDB Viral Integration Site DataBase

VIS ID

TVIS10005193

Fusion event

HBV-ZBTB20 integration

Validated

No

Detection method

PCR and Ultra-deep sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Start

2011

Orient

-

Integrated sequence

CCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTG| |TATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCT

Chromosome

chr3

Cytoband

q13.31

Reference genome

Start

End

114307598/114588751 (Hg38)

Orient

+

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-181b-5p ; hsa-mir-578 ; hsa-mir-4762-3p ; hsa-mir-526b-5p ; hsa-mir-4670-3p ; hsa-mir-29a-5p ; hsa-mir-513a-5p ; hsa-mir-4696 ; hsa-mir-577 ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-340-5p ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-27b-3p ; hsa-mir-216a-3p ; hsa-mir-27a-3p ; hsa-mir-144-3p ; hsa-mir-4789-5p ; hsa-mir-190a-3p ; hsa-mir-3941 ; hsa-mir-410-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-5580-3p ; hsa-mir-574-5p ; hsa-mir-4672 ; hsa-mir-6867-5p ; hsa-mir-3177-5p ; hsa-mir-4302 ; hsa-mir-6768-5p ; hsa-mir-8064 ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-5193 ; hsa-mir-6832-3p ; hsa-mir-361-3p ; hsa-mir-4286 ; hsa-mir-1306-5p ; hsa-mir-511-3p ; hsa-mir-217 ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-2110 ; hsa-mir-3150a-3p ; hsa-mir-383-5p ; hsa-mir-409-3p ; hsa-mir-4271 ; hsa-mir-450a-2-3p ; hsa-mir-4640-5p ; hsa-mir-4683 ; hsa-mir-4725-3p ; hsa-mir-4726-5p ; hsa-mir-4772-5p ; hsa-mir-5681b ; hsa-mir-613 ; hsa-mir-6716-5p ; hsa-mir-6760-5p ; hsa-mir-6763-5p ; hsa-mir-6780b-5p ; hsa-mir-6810-5p ; hsa-mir-6857-5p ; hsa-mir-7515 ; hsa-mir-329-5p ; hsa-mir-432-3p ; hsa-mir-432-5p ; hsa-mir-4764-5p ; hsa-mir-4768-5p ; hsa-mir-6809-3p ; hsa-mir-6817-3p ; hsa-mir-6833-3p ; hsa-mir-6873-3p ; hsa-mir-7110-3p

Nearest miRNA

hsa-let-7g/Upstream/272182; hsa-mir-12124/Downstream/154694;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/236940, chr3-CpG: 119/Downstream/557838

Upstream sequence

acattttagataaaatattgtagtagttttggatgctgattcctttaccctctgtgggactttttgttgttgtttggttgtgtatttgattagggacttg

Downstream sequence

ctccactgtaggatacttctttctgttctgttcttccttatgctgaatcttaatccatattagtctgttctcatgctgctatgaagaaatacccaagact