Fusion event
HBV-chr19 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGC| |ATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGT
End
51247187/50743930 (Hg38)
Nearest miRNA
hsa-mir-10395/Upstream/810793; hsa-let-7e/Downstream/462999;
Upstream sequence
gaagccccctgaagccctcactggaagcagaacagatacaggtgccatgcttgtacagcctgcagaacagtgagccgaatacatctcttttctttatgaa
Downstream sequence
tgacgcagcctcagacattcctttatagtaatgcaaatggaataaaacacctactcaaatacactaattcgctacaggttgggcacagtggctcacgctt
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).