Basic Information
VIS ID
TVIS10005265
Fusion event
HBV-LOC107985783 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
2189
Orient
-
Integrated sequence
GAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTGGAAGACCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATATGGGCCTAAAAA| |TCAGACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGAAGAGAAACTGTTCTTGAGTATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCC
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
186864520/185999793 (Hg38)
End
186864520/185999793 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107985783
Nearest miRNA
hsa-mir-10b/Upstream/1620749; hsa-mir-1244-1/Downstream/2297699;
Nearest TSS
ENST00000437798/Upstream/193711; ENST00000477672/Downstream/81552;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/260610, chr2-CpG: 87/Downstream/485977
Junction sequence
CTTCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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