ATP10B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005311
Fusion event
HBV-ATP10B integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1560
Orient
+
Integrated sequence
GTCTCGGGGCCGTTTGGGGCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCT| |TCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAG
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
160286734/160859727 (Hg38)
End
160286734/160859727 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATP10B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10397/Upstream/374277; hsa-mir-103a-1/Downstream/7306118;
Nearest TSS
ENST00000502646/Upstream/7513; ENST00000518888/Downstream/78899;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/437621, chr5-CpG: 68/Downstream/687959
Junction sequence
TTCTGTATAGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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