Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005357
Fusion event
HBV-C2orf72 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1827
Orient
+
Integrated sequence
GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTT
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
End
231914422/231049707 (Hg38)
Orient
+
Location type
Exon
Target gene
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-181d-3p ; hsa-mir-3065-3p ; hsa-mir-7112-5p ; hsa-mir-4666a-5p ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-600 ; hsa-mir-634 ; hsa-mir-3619-3p ; hsa-mir-3690 ; hsa-mir-4776-5p ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-377-3p ; hsa-mir-3713 ; hsa-mir-342-3p ; hsa-mir-574-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6878-3p ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p
Nearest miRNA
hsa-mir-10b/Upstream/3577520; hsa-mir-1244-1/Downstream/313001;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/11300, chr2-CpG: 48/Downstream/2869
Upstream sequence
GGTACTAATCTTTCTAATATGGCAGTGGTTGTGGCACTTCTGACTTGAATTGATAATTCTCATATCTAATAAAACCAAGAAGTACCTCGTTGATATCTTA
Downstream sequence
TAGAAAACAAAATGGATCTTCTTCATTCTCCTAAGGGGCTCCTTGCAGAGAGACCCTGGAGAGCAGGGAAGCTTGGCAAATGGTGGAAATCTGTGGCCTG
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).