Fusion event
HBV-FN1 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACTGGATGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCC| |GATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCAAAACTTATCGGGACTGACAACTCTGTTGTCCTCTCTCGGAAATAC
End
216299860/215435137 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1676978; hsa-mir-1244-1/Downstream/2465376;
Upstream sequence
ATGCAAGGAACTTAAATATTCTTTTGGAGTAATAGTCAAAAAGGACAACTTTAAGCAGCTTTCTCAAAGCAAAAGGAGGGTGTGTCTTTGAAAAACGGAA
Downstream sequence
AGAATTCCAACCTCTGTTCTTGGTGAAGTATCCTGAGCGGCCCTAAAGAGGTCTGAACCAATTACATCTCTTCCAAGTTAGTTAGAAACAAGACAGCTAT
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).