VISDB Viral Integration Site DataBase

VIS ID

TVIS10005393

Fusion event

HBV-DDI2 integration

Validated

No

Detection method

PCR and Ultra-deep sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Start

1800

Orient

+

Integrated sequence

GCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCT| |GTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGC

Chromosome

chr1

Cytoband

p36.21

Reference genome

Start

End

15959748/15633253 (Hg38)

Orient

+

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-484 ; hsa-mir-7-5p ; hsa-mir-1227-5p ; hsa-mir-3151-5p ; hsa-mir-128-2-5p ; hsa-mir-128-1-5p ; hsa-mir-6845-5p ; hsa-mir-6762-5p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-194-3p ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-5586-5p ; hsa-mir-3159 ; hsa-mir-1296-3p ; hsa-mir-4700-3p ; hsa-mir-137 ; hsa-mir-367-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-140-3p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-5006-3p ; hsa-mir-4446-5p ; hsa-mir-4755-5p ; hsa-mir-489-3p ; hsa-mir-642a-5p ; hsa-mir-3913-3p ; hsa-mir-4277 ; hsa-mir-5584-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-5582-5p ; hsa-mir-3910 ; hsa-mir-3714 ; hsa-mir-551b-5p ; hsa-mir-506-3p ; hsa-mir-124-3p ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-1295a ; hsa-mir-145-5p ; hsa-mir-15a-3p ; hsa-mir-1825 ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-4717-5p ; hsa-mir-5195-3p ; hsa-mir-548p ; hsa-mir-5704

Nearest miRNA

hsa-mir-12136/Upstream/3054230; hsa-mir-101-1/Downstream/1225696;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/15392, chr1-CpG: 91/Downstream/50830

Upstream sequence

cctaggctcaaacggtcctcccacctcagcctcccaaagtgtcgagattataggcatgagctaccacacccagccACAAATACTTTCTTTACACTGAATT

Downstream sequence

TAAATGATGAAATAGCCTTGACTCAGAGAACAGAAAGTAAATGTAATTGCTCATTTTAAATAAGCTTTAGGCATCCTCTCTGCATCTCTTACAGATGTAG