Basic Information
VIS ID
TVIS10005408
Fusion event
HBV-SLC47A1P1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1820
Orient
-
Integrated sequence
GTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAA
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
19485522/19582209 (Hg38)
End
19485522/19582209 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC47A1P1
Nearest miRNA
hsa-mir-1180/Upstream/237635; hsa-mir-10226/Downstream/7711701;
Nearest TSS
ENST00000595228/Upstream/9412; ENST00000580550/Downstream/15713;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/1835, chr17-CpG: 100/Downstream/65822
Junction sequence
TATT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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