Basic Information
VIS ID
TVIS10005409
Fusion event
HBV-SLC47A1P1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
3198
Orient
+
Integrated sequence
ATTGACAACAGTGCCAGCAGCGCCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGACAGCCTACTCCCATCTCTCCACCTCTAAGAGACAGTCATCCT| |CAGGCCATGCAGTGGAA
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
19487606/19584293 (Hg38)
End
19487606/19584293 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC47A1P1
Nearest miRNA
hsa-mir-1180/Upstream/239719; hsa-mir-10226/Downstream/7709617;
Nearest TSS
ENST00000595228/Upstream/11496; ENST00000580550/Downstream/13629;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/3919, chr17-CpG: 100/Downstream/63738
Junction sequence
GATATTGAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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