Basic Information
VIS ID
TVIS10005433
Fusion event
HBV-FLJ39630 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1787
Orient
+
Integrated sequence
GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG
Host Sequence
Chromosome
chr8
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
63280969/62368410 (Hg38)
End
63280969/62368410 (Hg38)
Orient
-
Location type
Intron
Target gene
FLJ39630
Nearest miRNA
hsa-mir-124-1/Upstream/653551; hsa-mir-10400/Downstream/2010739;
Nearest TSS
ENST00000518652/Upstream/119447; ENST00000622794/Downstream/105859;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/118905, chr8-CpG: 91/Downstream/670153
Upstream sequence
GAGAGAAAACTTATAACTTTGAAGCAATATTAGACCAAGAGAAAAATTTTCTACTTAAGGCTTATCAGCAATTGTACCTGACTGCTATTAATAGAACTGA
Downstream sequence
tgatttttgacaaatgtgttgagaacacacacagaaaggatcatctttttaataaatggtgttggaacacctcaatatccacatgcaCgtgaaagttgtc
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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