Basic Information
VIS ID
TVIS10005445
Fusion event
HBV-chr13 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1821
Orient
+
Integrated sequence
TTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAA
Host Sequence
Chromosome
chr13
Cytoband
q14.2
Reference genome
End
47940280/47366145 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-2276/Upstream/3169945; hsa-mir-1267/Downstream/2630270;
Upstream sequence
ggttactttgtatccattttgtcaatctgtactttttatttgaatgcttaatcatttatatttaatgtaattattgataaggtagaatttatatggacaa
Downstream sequence
tttctgttTTTAAAAAATATTAATTGGCCAAGATTTAAGTTATGCTTACTGTTTATGGGGTGCTTTGAGGttttttattattatactttaagttctggga
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate