Fusion event
HBV-SGCD integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGC| |ACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAG
End
155791875/156364865 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/1535325; hsa-mir-103a-1/Downstream/4109537;
Upstream sequence
aaagcaagtctggataaattttaaaaaatgaaatcatatcaagcacactcttagatctcaatgtaatcaaaatataaataaataccaacatctctcaaca
Downstream sequence
ttaggacatttgagttatggtctgggctttttcacaagctatgagaccttgggcatactacctgtcgcctctgggcatcatggtgcatgttggtaaaacg
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).