TEKT3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005490
Fusion event
HBV-TEKT3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1818
Orient
+
Integrated sequence
TTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
15243373/15340056 (Hg38)
End
15243373/15340056 (Hg38)
Orient
-
Location type
Exon
Fragile sites / regions
FRA17A
Target gene
TEKT3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1253/Upstream/88360; hsa-mir-10226/Downstream/941958;
Nearest TSS
ENST00000595228/Upstream/1500; ENST00000584540/Downstream/1537;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/76867, chr17-CpG: 36/Downstream/1332
Upstream sequence
gatggtatataaattattacactttggagagctagatggtggtatccagtaaagttgaaatggcaaattacctgtgactcagcaattcaatttcttggta
Downstream sequence
tgtacctagagaaatgcaaatatgtttacaattagaatgtacaagaattcctttctagtatttttaaagggagcaaactaaaagtccatcaacaggagga
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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