Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005542
Fusion event
HBV-MON2 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2831
Orient
+
Integrated sequence
CAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGG| |GAACAAGAGCTACAGCATGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAATCTTTCTGTTCCCAATCCTCTGGGATTCTTTCCCGATCAC
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
Start
End
62935481/62541701 (Hg38)
Orient
+
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-21-5p ; hsa-mir-4684-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-6771-3p ; hsa-mir-105-5p ; hsa-mir-1262 ; hsa-mir-20a-3p ; hsa-mir-217 ; hsa-mir-340-3p ; hsa-mir-3646 ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4701-3p ; hsa-mir-616-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6807-3p ; hsa-mir-6827-3p ; hsa-mir-6849-3p ; hsa-mir-7853-5p ; hsa-mir-3675-3p ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-1228/Upstream/281247; hsa-let-7i/Downstream/61985;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/74626, chr12-CpG: 165/Downstream/60678
Junction sequence
A
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).