Basic Information
VIS ID
TVIS10005552
Fusion event
HBV-chr16 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2703
Orient
+
Integrated sequence
ACAGTTAATGAAAAAAGGAGATTAAAATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATT| |ATCCTGAACATGCAGTTAATCATTACTTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGC
Host Sequence
Chromosome
chr16
Cytoband
q11.2
Reference genome
End
46405404/46390378 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/12226705; hsa-mir-11401/Downstream/3902238;
Upstream sequence
ccattttaggatttgattcgagtcctttcgatgattccattcgattccactcgatgatgatttcattcgagtccattcgacacttccaatcgattccatt
Downstream sequence
tgatgtttccattcgagtccaattgatgattccattcaattccattcgatgatgattccgtacgattccattctgtgatgattccatgtgattgcattca
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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