VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10005564

Fusion event

HBV-ZBTB8A integration

Validated

No

Detection method

PCR and Ultra-deep sequencing

Data source

Curated

Sample type

Nontumor

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

29861854

Virus Sequence

Virus name

HBV

Reference genome

AP011098

Start

2687

Orient

-

Integrated sequence

ATATGTGGGCCCTCTTACAGTTAATGAAAAAAGGAGATTAAAATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAA| |GGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAG

Host Sequence

Chromosome

chr1

Cytoband

p35.1

Reference genome

GRCh37/hg19

Start

33005229/32539628 (Hg38)

End

33005229/32539628 (Hg38)

Orient

+

Location type

Intron

Target gene

ZBTB8A

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-130b-3p ; hsa-mir-103a-3p ; hsa-mir-21-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-1304-5p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-6879-3p ; hsa-mir-6880-5p ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-6812-3p ; hsa-mir-500b-3p ; hsa-mir-106a-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-6722-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-652-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130a-3p ; hsa-mir-4520-2-3p ; hsa-mir-4520-3p ; hsa-mir-7703 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-4538 ; hsa-mir-4267 ; hsa-mir-4453 ; hsa-mir-508-5p ; hsa-mir-5093 ; hsa-mir-4708-3p ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-2276-3p ; hsa-mir-1252-3p ; hsa-mir-4635 ; hsa-mir-6798-5p ; hsa-mir-6783-5p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-1288-5p ; hsa-mir-3190-5p ; hsa-mir-339-5p ; hsa-mir-3926 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4684-5p ; hsa-mir-4768-3p ; hsa-mir-4786-5p ; hsa-mir-548c-3p ; hsa-mir-548s ; hsa-mir-593-3p ; hsa-mir-6732-3p ; hsa-mir-6818-3p ; hsa-mir-6849-3p ; hsa-mir-6895-3p ; hsa-mir-143-5p ; hsa-mir-4534 ; hsa-mir-5698 ; hsa-mir-6499-3p ; hsa-mir-6514-5p ; hsa-mir-8082

Nearest miRNA

hsa-mir-12136/Upstream/452621; hsa-mir-101-1/Downstream/792765;

Nearest TSS

ENST00000473358/Upstream/199; ENST00000465780/Downstream/92430;

Nearest CpG islands

chr1-CpG: 106/Target, None/Upstream, None/Downstream

Junction sequence

TTTAACACCG

* Color: Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence

Reference

Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).