MYO1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005599
Fusion event
HBV-MYO1B integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1676
Orient
+
Integrated sequence
GTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCA| |GCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAG
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
192242166/191377440 (Hg38)
End
192242166/191377440 (Hg38)
Orient
+
Location type
Intron
Target gene
MYO1B
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-378a-5p ; hsa-mir-363-3p ; hsa-mir-4703-3p ; hsa-mir-145-3p ; hsa-mir-6780b-3p ; hsa-mir-4698 ; hsa-mir-7852-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-3646 ; hsa-mir-561-3p ; hsa-mir-3662
Nearest miRNA
hsa-mir-10b/Upstream/2244329; hsa-mir-1244-1/Downstream/15405794;
Nearest TSS
ENST00000437798/Upstream/7876; ENST00000496992/Downstream/82;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/131226, chr2-CpG: 88/Downstream/300407
Upstream sequence
GGGTAAGACAGTAGAGAAAAATTGCATACTTGGAGCATGGGTGGAAAACTGGAGAGAGGAGATGAGTCATTCCTGGGGCAAGTTCCTGCCCACTTCCTCT
Downstream sequence
TCTGGAGACTTTGATTCATGAGCCTGACACGTGGGAGAGGGCCTGGCTCAGGGATTGCTGGCTATTCACACAGTTCTTGACAAACCAAAAAAGTCTCCAC
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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