RFTN1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005606
Fusion event
HBV-RFTN1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
277
Orient
-
Integrated sequence
CCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTT| |CTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTATCGCTGGA
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
End
16376931/16335424 (Hg38)
Orient
+
Location type
Intron
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12127/Upstream/461575; hsa-let-7g/Downstream/597772;
Upstream sequence
tttgccacatgaggtgatatcaaggttctgaggtttagcaaatgaatggatgattttgagggccaccactcTCCACCCTCTACACTTGGTGGCTTggcct
Downstream sequence
tgcagccttaaaaaggaacgaatcacgtcctttgtggggacatggatggagctggaagctgttatccttagcaaactaacgcaggaacagaaaatcaaac
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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