NAALADL2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005609
Fusion event
HBV-NAALADL2 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1835
Orient
-
Integrated sequence
GGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCC| |TAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTC
Host Sequence
Chromosome
chr3
Cytoband
q26.31
Reference genome
GRCh37/hg19
Start
174686290/174968500 (Hg38)
End
174686290/174968500 (Hg38)
Orient
-
Location type
Intron
Target gene
NAALADL2
Nearest miRNA
hsa-let-7g/Upstream/3861741; hsa-mir-1224/Downstream/401040;
Nearest TSS
ENST00000440867/Upstream/104684; ENST00000414826/Downstream/155906;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/526942, chr3-CpG: 133/Downstream/2227949
Upstream sequence
tgaaaccctgtctctactaaaaaatacaaaaaaaattagctgggcgtggtggtcggtgcctgtagtcccagctactagggaggctgattcaggtgaatgg
Downstream sequence
CTATTTTTTTTTtctatcacccaggctgcagtgtagtgacatgatctcagctcactgcaacctctgcctcccaggtttaagcaattctcctgcctcagcc
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate