Basic Information
VIS ID
TVIS10005620
Fusion event
HBV-chr6 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1812
Orient
+
Integrated sequence
GACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGAC
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
End
16972021/16971790 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/830166; hsa-mir-10398/Downstream/1599994;
Upstream sequence
tgaaacactctttctgtagaatctgcaagtggataattggaccgccttgaggccttcgttggaaacgggatttcttcatgttactctagatagaagaatt
Downstream sequence
catacaaaaagatacatatttaacacattggactggttgtatggggagactggaataggaaatatggataaaagggattttaaaaagtaaagagggacct
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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