GTF2I _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005628
Fusion event
HBV-GTF2I integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1867
Orient
-
Integrated sequence
TTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAA| |GCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACT
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
End
74145259/74730921 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/134895; hsa-mir-10399/Downstream/1184276;
Upstream sequence
CTGTTTTCCATTGATTTTGAATACATCAGAATCTATTGCCAGTTTTTGATTGTTTATTTAGTAGGCCATAAGAAAGATTCAAGTTTACTTCCATTTTGCA
Downstream sequence
gtctcaaactcctgacctcaagtgatcctcccgccttggcctcccaaagtgctggcattacaggcgtgagccacccttcccggccACTGCTTTTATCTTG
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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