Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005634
Fusion event
HBV-ZMYM4 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1743
Orient
+
Integrated sequence
AAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGG| |GGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATC
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
Start
End
35838761/35373160 (Hg38)
Orient
-
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-3149 ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6789-3p ; hsa-mir-4707-3p ; hsa-mir-4258 ; hsa-mir-4438 ; hsa-mir-34a-5p ; hsa-mir-34c-5p ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-4698 ; hsa-mir-4705 ; hsa-mir-548au-3p ; hsa-mir-551b-5p ; hsa-mir-7150 ; hsa-mir-8063
Nearest miRNA
hsa-mir-12136/Upstream/703466; hsa-mir-101-1/Downstream/1788403;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/103906, chr1-CpG: 95/Downstream/183919
Junction sequence
TTATCTC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).