Fusion event
HBV-chr9 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
AGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGAC| |GAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATCCCTTGGACTCATAAGGTGGGAAACTTTACTGGGCTTTATT
End
26327102/26327104 (Hg38)
Nearest miRNA
hsa-mir-101-2/Upstream/4814919; hsa-let-7a-1/Downstream/2536522;
Upstream sequence
tagcacatcaattatattgcttttctaaaaaaaaatttagtgcttttcctagattttgcaatatacacttacaactaaatacattttcaaataactctat
Downstream sequence
GAGGACTAAAATGCTTCTGATTGGAGTGTAAAAGCAGGGGAAAATGAGATTCATATGTGCTATAATGTTGTCTAATGTTTCCACTCTAGTTCCTTAAGTA
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).