Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005659
Fusion event
HBV-TPPP integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1751
Orient
+
Integrated sequence
ACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAG| |ATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTC
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
Start
End
676981/676866 (Hg38)
Orient
-
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-26b-5p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-5589-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-548c-3p ; hsa-mir-410-3p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-6832-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-377-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-4635 ; hsa-mir-149-3p ; hsa-mir-215-3p ; hsa-mir-2467-3p ; hsa-mir-2467-5p ; hsa-mir-3186-3p ; hsa-mir-4728-5p ; hsa-mir-6773-3p ; hsa-mir-6781-5p ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-7112-5p ; hsa-mir-760
Nearest miRNA
hsa-mir-10397/Downstream/386030;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/8392, chr5-CpG: 26/Downstream/832
Junction sequence
CGTAGGTT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).