Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005665
Fusion event
HBV-GUSBP3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2775
Orient
-
Integrated sequence
CCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTC| |TATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAGCTACAGCATGGGAGGTTGGTCTTCCAAACCTCGAC
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
Start
End
69702129/70406302 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/10702599; hsa-mir-103a-1/Downstream/1763165;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/356308, chr5-CpG: 39/Downstream/8827
Upstream sequence
cgcgcggaggaggcggagctggaaggtgaaggggcaggacgggTGCCCGGGTCCCCAGTCCCTCCGCCACGTGGGAAGCGCGGTCCTGGGCGTCTGTGCC
Downstream sequence
gttgagagatgttgatatttatttatattttgattacattgagatctaagagtgtgcttgatatgatttcattttttaaaatttatccagacttgcttta
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).