TXNL4B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005721
Fusion event
HBV-TXNL4B integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2028
Orient
-
Integrated sequence
GAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGA| |GTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTG
Host Sequence
Chromosome
chr16
Cytoband
q22.2
Reference genome
End
72095215/72061316 (Hg38)
Orient
-
Location type
Promoter
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/2030894; hsa-mir-11401/Downstream/4807620;
Upstream sequence
ACTGATTGAGTGCCTATTGAATGCTAGGTCCCAGAAAGTTAactgttgtccttgttttacagacaaggaaacagagactcagagatggtaagtgagttgc
Downstream sequence
ttaaggttacatagctatgaaacagggaagcagaactttgaacccaggtctgtttgatacaaactcagaggtcctttcactgcatgctgttgcctcctcA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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