hsa-mir-550a-3-5p _LIHC.png
EHHADH _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005732
Fusion event
HBV-EHHADH integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1494
Orient
+
Integrated sequence
CAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGGCTCTACCGTCCCCTT| |CTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCAC
Host Sequence
Chromosome
chr3
Cytoband
q27.2
Reference genome
GRCh37/hg19
Start
184963339/185245551 (Hg38)
End
184963339/185245551 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
FRA3C
Target gene
EHHADH
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-550b-2-5p ; hsa-mir-328-3p ; hsa-mir-6807-5p ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-6851-3p ; hsa-mir-6775-3p ; hsa-mir-1291 ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-4252 ; hsa-mir-6889-3p
Nearest miRNA
hsa-let-7g/Upstream/1004062; hsa-mir-1248/Downstream/7659;
Nearest TSS
ENST00000440867/Upstream/10089; ENST00000438798/Downstream/8480;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/91857, chr3-CpG: 43/Downstream/8302
Upstream sequence
TTTTAGCTCTTAACATGTAATTCTGAAATCCAACCACCATGTTTCACAAATCCATATCTACTTATGTTCTTCCTAGGTTTTTAGGTGTATTAGAAATGAC
Downstream sequence
TTTCACACTGTAGGAAATAAGAGTTGCATGTCCTTCTGCAGGATTGTGTCCAGTGATCAGCATGTGTGACAAGTGACATACTCCTTGATAAATCTTAAGA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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