Fusion event
HBV-NDUFC2-KCTD14 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATA| |AATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGG
End
77764225/78053179 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/2717993; hsa-let-7a-2/Downstream/1348843;
Upstream sequence
taattttttttgtgtgtgtatttttagtagagatggggtttcaccatgttgaccgggctggtctcgaactcctgacctcaagtgatccacctgtgctggg
Downstream sequence
tgtgagccactgcacctggccTCGTtaccttattttcttcctagtacaagtcacaatgtgatgttaaccatattgatctgtgcattgttggtcattgctc
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).