Fusion event
HBV-chr13 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGAC
End
89536203/88883949 (Hg38)
Nearest miRNA
hsa-mir-1297/Upstream/1265209; hsa-mir-1267/Downstream/1347233;
Upstream sequence
attaactgttgaatatttcatgtaccatattgaatgctgtactgaaagtaaaaaacagaatggttgtttgggtactcaaagtatgatttctactgaatct
Downstream sequence
gtactgctttcacattattgtaaagtcaaaaatttgcaagtctaatcatcctaagatgagcaccatctgtatatataacataaaattttgggttggcagt
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).