Basic Information
VIS ID
TVIS10005795
Fusion event
HBV-LINC01924 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1829
Orient
-
Integrated sequence
CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACC| |TCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGG
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
62003057/64335822 (Hg38)
End
62003057/64335822 (Hg38)
Orient
+
Location type
Intron
Target gene
LINC01924
Nearest miRNA
hsa-mir-1-2/Upstream/5884664; hsa-mir-5011/Downstream/2745762;
Nearest TSS
ENST00000575820/Upstream/75767; ENST00000578545/Downstream/789888;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/332801, chr18-CpG: 88/Downstream/1414778
Upstream sequence
TAATTACCTTCTGATACAAACAAGTGTCCTTGTGAAGGCTAAAAATAAACAGGATGGAGTTAGGCCAGACACCATCATAGTAAGACTTTTAGAGACAGAC
Downstream sequence
ATTTCATTCCAAAAATTGAGTCTTGAATATAAAACTCTCTTTTTGGTTATCTAAGCACTAAGTCCACATACACAGGAGTCTATGAGTCTAATGTTTCCTT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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