Basic Information
VIS ID
TVIS10005802
Fusion event
HBV-chr2 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1813
Orient
+
Integrated sequence
ACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACC
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
End
227132279/226267563 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/1257023; hsa-mir-1244-1/Downstream/391147;
Upstream sequence
TCCACCTTTGAGAAGCTGAGGTAGTCTGAGATTGACAACTAtctggcttctcatgagctcttagcacaggcaaagattctattttcctgaccctctggaa
Downstream sequence
gttaagcttggccatgaaactttactctggccacggaactttcctctgggcactgacataggggcagaagtgattcatgtcattcctgggtggaagcaca
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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