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VISDB
Viral Integration Site DataBase
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TVIS10005820
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005820
Fusion event
HBV-CDK13 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1822
Orient
-
Integrated sequence
TTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAG
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
40044263/40004664 (Hg38)
End
40044263/40004664 (Hg38)
Orient
-
Location type
Intron
Target gene
CDK13
miRNAs that regulate target gene
hsa-mir-133b
;
hsa-mir-29b-2-5p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-664b-3p
;
hsa-mir-579-3p
;
hsa-mir-5696
;
hsa-mir-664a-3p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-8061
;
hsa-mir-4760-5p
;
hsa-mir-6794-3p
;
hsa-mir-376a-5p
;
hsa-mir-372-5p
;
hsa-mir-888-5p
Nearest miRNA
hsa-mir-1183/Upstream/3085232; hsa-mir-10399/Downstream/3146231;
Nearest TSS
ENST00000635602/Upstream/5275;
ENST00000642592/Downstream/41266;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/52651
,
chr7-CpG: 109/Downstream/129618
Junction sequence
CA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Sample Information
×
Sample name
RK141_NT
Sample type
Nontumor
Age
31
Gender
Female
CpG Island Information
×
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