CPA6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005838
Fusion event
HBV-CPA6 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1805
Orient
+
Integrated sequence
CTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA
Host Sequence
Chromosome
chr8
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
68545532/67633297 (Hg38)
End
68545532/67633297 (Hg38)
Orient
-
Location type
Intron
Target gene
CPA6
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-124-1/Upstream/3254040; hsa-mir-10400/Downstream/6915246;
Nearest TSS
ENST00000518652/Upstream/180647; ENST00000526382/Downstream/99290;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/289482, chr8-CpG: 64/Downstream/318893
Junction sequence
GC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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