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VISDB
Viral Integration Site DataBase
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TVIS10005841
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005841
Fusion event
HBV-PLXDC2 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
163
Orient
-
Integrated sequence
TGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACAGAACATGGAGAGC| |ACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGA
Host Sequence
Chromosome
chr10
Cytoband
p12.31
Reference genome
GRCh37/hg19
Start
20525538/20236609 (Hg38)
End
20525538/20236609 (Hg38)
Orient
-
Location type
Intron
Target gene
PLXDC2
miRNAs that regulate target gene
hsa-mir-148b-3p
;
hsa-mir-1-3p
;
hsa-mir-181a-5p
;
hsa-let-7b-5p
;
hsa-mir-573
;
hsa-mir-3616-5p
;
hsa-mir-3152-3p
;
hsa-mir-4635
;
hsa-mir-4694-5p
;
hsa-mir-574-5p
;
hsa-mir-1277-5p
;
hsa-mir-599
;
hsa-mir-3912-5p
;
hsa-mir-3924
;
hsa-mir-190a-3p
;
hsa-mir-6755-3p
;
hsa-mir-6867-5p
;
hsa-mir-223-5p
;
hsa-mir-198
;
hsa-mir-193a-5p
;
hsa-mir-1273f
;
hsa-mir-1304-3p
;
hsa-mir-4781-3p
;
hsa-mir-5011-5p
;
hsa-mir-3976
;
hsa-mir-4789-3p
;
hsa-mir-8485
;
hsa-mir-302f
;
hsa-mir-3675-3p
;
hsa-mir-136-3p
;
hsa-mir-5698
;
hsa-mir-744-3p
;
hsa-mir-6805-3p
;
hsa-mir-5691
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-143-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-3622b-5p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-3194-3p
;
hsa-mir-6499-3p
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-103b
;
hsa-mir-5693
;
hsa-mir-7705
;
hsa-mir-617
;
hsa-mir-3605-3p
;
hsa-mir-8087
;
hsa-mir-6854-5p
;
hsa-mir-6885-3p
;
hsa-mir-147a
;
hsa-mir-5010-3p
;
hsa-mir-6818-5p
Nearest miRNA
hsa-mir-1265/Upstream/2391416; hsa-mir-107/Downstream/315361;
Nearest TSS
ENST00000439456/Upstream/144825;
ENST00000417845/Downstream/579216;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/418592
,
chr10-CpG: 149/Downstream/936590
Junction sequence
TTCT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Sample Information
×
Sample name
RK147_NT
Sample type
Nontumor
Age
50
Gender
Male
CpG Island Information
×
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