Basic Information
VIS ID
TVIS10005863
Fusion event
HBV-chr13 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
728
Orient
+
Integrated sequence
GCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGC| |TTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTTTACCTCTATTACCAATTTTCTTTTGTCTTTGGGTATA
Host Sequence
Chromosome
chr13
Cytoband
q33.1
Reference genome
End
103554265/102901915 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/855911; hsa-mir-1267/Downstream/4629256;
Nearby gene
METTL21EP(-5882) ;
Upstream sequence
cctcacggaggccatgagcccagtgcagatgggcagaggcagaactggggatggcctggtagggggaatacatgaaaaccaatcagtgctaggtgtcctg
Downstream sequence
gcagggggagcttaacccacaaccagggcacagtgagggcttctgagggaaggtttagctgggtgaaggagatggaggtgagggcagagaggagagacgg
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate