Fusion event
HBV-chr13 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGC| |TTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTTTACCTCTATTACCAATTTTCTTTTGTCTTTGGGTATA
End
103554265/102901915 (Hg38)
Nearest miRNA
hsa-mir-1297/Upstream/855911; hsa-mir-1267/Downstream/4629256;
Upstream sequence
cctcacggaggccatgagcccagtgcagatgggcagaggcagaactggggatggcctggtagggggaatacatgaaaaccaatcagtgctaggtgtcctg
Downstream sequence
gcagggggagcttaacccacaaccagggcacagtgagggcttctgagggaaggtttagctgggtgaaggagatggaggtgagggcagagaggagagacgg
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).