Basic Information
VIS ID
TVIS10005924
Fusion event
HBV-chr8 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2023
Orient
-
Integrated sequence
ATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCC| |TTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTA
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
End
82361761/81449526 (Hg38)
Orient
-
Location type
Promoter
Nearest miRNA
hsa-mir-12123/Upstream/1208053; hsa-mir-10400/Downstream/9755959;
Nearby gene
PMP2(-2003) ; FABP9(+8857) ;
Upstream sequence
gtgaatctaaacatatctaaacatagaggttgggcgaggtggctcacgcctgtaatcccagcactttgggaggccaatgcaggcagatcacttgaggtca
Downstream sequence
CCAGACAAGTTTGGACCGTGATGGGATTCTGAGGCCAATATATGGGCCAAAGGCACAGATCAAAGCAATGAGGGAAGACCCGGACTGAACTAGGCCTGAA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate