NTNG1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10005932
Fusion event
HBV-NTNG1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1823
Orient
-
Integrated sequence
TAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGA
Host Sequence
Chromosome
chr1
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
107951805/107409183 (Hg38)
End
107951805/107409183 (Hg38)
Orient
+
Location type
Intron
Target gene
NTNG1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-129-5p ; hsa-mir-2054 ; hsa-mir-3613-5p ; hsa-mir-6885-3p
Nearest miRNA
hsa-mir-101-1/Upstream/7127875; hsa-mir-11399/Downstream/488040;
Nearest TSS
ENST00000473358/Upstream/148380; ENST00000438318/Downstream/264466;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/267342, chr1-CpG: 22/Downstream/71427
Upstream sequence
CTTTGTGATCTTGTTGAAACAGCATCAGTGTTAAAAACTTGCAAATGAAAACCTTCAGCTCTAATAGTCTAATTTTTCTGCTTTAGTATCCCCCTTGGCA
Downstream sequence
TTTGCCTAACTGTATATATACCCCACAATGTGCTCCTTTCAGGCCTTGACAATTGCATTTGCACGTGCATTTTAGTGCAACAGGGAAGCAAGTAGAAGCA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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