Basic Information
VIS ID
TVIS10005957
Fusion event
HBV-chr14 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1793
Orient
+
Integrated sequence
CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT
Host Sequence
Chromosome
chr14
Cytoband
q21.1
Reference genome
End
41785355/41316152 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/4363761; hsa-mir-1185-1/Downstream/6444843;
Upstream sequence
TTGCAGCTAAACAagagctaagacaataggaaaaaatattccctgaagtggaagtgtaaaggaaagactcaaaaccaagggtaggtacacattgagataa
Downstream sequence
atcttctggcacaccaaccatcacaataaacacaaggtaacactagcaaaatttgaagcctatggtattctgagggtaactgtagcaaaaatagttccca
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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